AB Antalica

Китове за Real Time PCR

Бактерии и Паразити

BOR SL- Kit for the detection of Borrelia burgdorferi sensu lato. Target region (nested PCR): p66 gene.
CHLAM T- Kit for the detection of Chlamydia trachomatis. Target region (nested PCR): cryptic plasmid.
HP -Kit for the detection of Helicobacter pylori. Target regions: ure A and cag A.
MB – Kit for the detection of Mycobacterium tuberculosis. Target region: insertion sequence IS6110 (exIS986)
PCP – Kit for the detection of Pneumocystis carinii. Target region: rRNA 5S.
TOXO – Kit for the detection of Toxoplasma gondii. Target region (nested PCR): B1 gene.

Вируси

B19 – Kit for the detection of Human Parvovirus (B19). Target region: nucleotides 1390-1608 of B19 genome.
CMV – Kit for the detection of Human Cytomegalovirus. Target region (nested PCR): UL122 gene.
EBV – Kit for the detection of Epstein-Barr Virus. Target region (nested PCR): gp 220.
HBV – Kit for the detection of Hepatitis B virus. Target region (nested PCR): CORE region.
HCV-PM Bio Kit for the detection of Hepatitis C virus. Target region (nested premixed RT-PCR): 5’UTR.
HCV-TS- Kit for Hepatitis C virus typing by reverse hybridization on strips, starting from 5′ UTR PCR product.
HHV-6- Kit for the detection of Human Herpesvirus 6. Target region (nested PCR): ORF U3.
HHV-8 – Kit for the detection of Human Herpesvirus 8. Target region (PCR and RT-PCR): ORF K8.1.
HSV 1/2 – Kit for the detection of Human Herpesvirus type 1 and 2 by multiplex PCR. Target region (nested multiplex PCR): glycoproteins D and G.

HUMAN PAPILLOMAVIRUS

HPV-HS Bio – Human Papillomavirus high-sensitivity screening and typing. Target region: protein L1 gene.
HPV-TYPE – Human Papillomavirus screening and typing by reverse hybridization on strips, starting from the
biotinylated PCR product. The kit can be used with the biotynilated product obtained with the kits HPV-HS-Bio cod.03-23A and 03-23R.
HPV TYPE EXPRESS- Rapid system for screening and typing of Human Papillomavirus by allele-specific reverse hybridization on strip.
HPV – Human Papillomavirus screening and typing. It can detect at least 70 genotypes and type 32 of them by RFLP. Target region: protein L1

Амплификационни китове за детекция

Бактерии и Паразити

Вируси

HUMAN PAPILLOMAVIRUS

HPV-HS Bio – Human Papillomavirus high-sensitivity screening and typing.
Target region: protein L1 gene.
HPV-TYPE – Human Papillomavirus screening and typing by reverse hybridization on strips, starting from the
biotinylated PCR product. The kit can be used with the biotynilated
product obtained with the kits HPV-HS-Bio cod.03-23A and 03-23R.
HPV TYPE EXPRESS- Rapid system for screening and typing of Human Papillomavirus
by allele-specific reverse hybridization on strip.
HPV – Human Papillomavirus screening and typing. It can detect at least 70 genotypes and type 32 of them by RFLP. Target region: protein L1 gene.
HPV SCK – Cytological samples collection kit.
RI-HPV STAR- Kit for Human Papilloma Virus by Real Time PCR .

PCR Китове онкохематология, хематология, онкология, генетични заболявания, HLA

Генетични заболявания

AZF MX COMPLETE – Complete system for the detection of deletions at AZF locus, involved in male infertility. Target regions (multiplex amplification) sY86, DFFRY, DBY, sY95, sY117, sY125, sY127, sY254, sY84, sY134, SRY, ZFX/ZFY.
AZF-MX – Kit for the detection of deletions at AZF locus, involved in male infertility. Target regions (multiplex amplification) sY86, DFFRY, DBY, sY95, sY117, sY125, sY127, sY254, sY84, sY134, SRY, ZFX/ZFY.
AZF MX EXT – kit for the detection of the extension of the deletions at AZF locus involved in male infertility.
DDK/G17 – Kit for the detection of deletions in the Duchenne and Becker muscular dystrophy gene. Target regions exons 3, 4, 6, 8, 13, 17, 19, 43, 44, 45, 47, 48, 49, 50, 51, 52, 60.

DISEASE-ASSOCIATED POLIMORPHISMS

APO E – Kit for the detection of Apolipoprotein E gene polymorphisms by amplification and RFLP analysis. Target region: exon 4 of the ApoE gene (including codons 112 and 158).
COLI A1/SP1 – Kit for the detection of SP1 polymorphism in Collagen I gene (col I a1). Target region col Ia1 gene.OP- POL – Kit for the detection of some polymorphisms associated with osteoporosis (Vitamin D Receptor gene, Collagen Ia1 gene and Estrogen Receptor gene) by PCR amplification and restriction enzyme digestion
VDR – Kit for the detection of polymorphisms in the vitamin D receptor gene. Target region: vdr gene. HLA
AB CELIACHIA – Kit for determination of genetic predisposition for Celiac disease by selective amplification of HLA alleles related to DQ2 and DQ8 haplotypes.HLA-B*57:01 – Kit for HLA-B*57:01 typing for identification of subjects with pharmacogenetical risk related to Abacavir use.

Хематология

AB-THROMBO TYPE – Kit for the simultaneous identification of the most important mutations related to thrombosis by DNA amplification and reverse hybridization on strip. Factor V Leiden, G1691A (Arg505Gln); Factor II, G20210A; MTHFR C677T; MTHFR A1298C
AB-THROMBO TYPE PLUS – Kit for the simultaneous identification of mutations related to thrombosis by DNA amplification and reverse hybridization on strip. Factor V Leiden, G1691A (Arg505Gln); Factor II, G20210A; MTHFR C677T; MTHFR A1298C, PAI 1 4G/5G, Fattore V (HR2) H1299R.
HEMO STRIP – Kit for identification of mutations in HFE gene related to hemochromatosis by DNA amplification and reverse hybridization on strips. STR/VNTR – Kit for anaylsis of chimerism after allogenic bone marrow transplantation by Short Tandem Repeats (STR) and Variable Number of Tandem Repeats (VNTR).

Онкология

12-13 K RAS- Kit for the detection of k-ras oncogene mutations by amplification of DNA codon 12 and 13 regions) and RFLP analysis.
CC-MSI – Kit for the analysis of microsatellite instability in colon-rectal cancer by multiplex amplification with fluorescent primers and subsequent fragment analysis by automatic DNA sequencer.
P-53 – Kit for screening of p53 gene mutations by SSCP. Target regions: exons 5, 6, 7, 8 of p53 gene. Detection on polyacrylamide gel

Онкохематология

Y-TCR – Kit for the analysis of clonality of V-J regions od the gamma chain of T-cell receptor (TCR).
BCL-1 – Kit for the detection of the bcl-1 gene t(11,14) (q13;q32) translocation. Target regions: Major Translocation Cluster (MTC).
BCL-2 – Kit for the detection of the bcl-2 gene t(14;18) (q32;q21) translocation. Target regions (nested PCR): Major Break-Point Region (MBR) and minor cluster region (mcr).
BCR-ABL – Kit for the detection of the translocation t(9;22) (q34;q11), involving the abl protooncogene on chromosome 9 and the bcr gene on chromosome 22 (p210 M-bcr trascript).
BCR-ABL p190 – Kit for the detection of the translocation t(9;22) (q34;q11), involving the abl protooncogene on chromosome 9 and the bcr gene on chromosome 22 (p190 m-bcr transcript).
CPIG CDR I – Kit for the analysis of Ig heavy chain clonality (CDR I). Target regions: variable (V), hypervariable (H-CDR I) and junctions (J) regions.
CPIG CDR II – Kit for the analysis of Ig heavy chain clonality (CDR II). Target regions: variable (V), hypervariable (H-CDR II) and junctions (J) regions.
CPIG CDR III – Kit for the analysis of Ig heavy chain clonality (CDR III). Target regions: variable (V), hypervariable (H-CDR III) and junctions (J) regions.
JAK-2 – Kit for the detection of the mutation V617F in the gene Janus kinase (Jak-2) in mieloproliferative disorders by DNA amplification with ARMS system . Target region: exon 14 of Jak-2 gene (chromosome 9).